Carbamic chloride, N-methyl-N-phenyl- → HCID 69519021, compound

HRID 1831200Notes

Reaction equation

HRID 1831200 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:18])[CH2:10][O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:4][CH:3]=1.[CH3:19][N:20]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:21](Cl)=[O:22]>>[O:11]([CH2:10][C:9]([NH:8][C:5]1[CH:4]=[CH:3][C:2]([O:1][C:21](=[O:22])[N:20]([CH3:19])[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[CH:7][CH:6]=1)=[O:18])[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 836385HCID 836385, compound

Product 1

HCID 69519021HCID 69519021, compound

Procedure

The title product was prepared from N-(4-hydroxy-phenyl)-2-phenoxy-acetamide and N-methyl-N-phenylcarbamoyl chloride. The crude product was purified by preparative HPLC (54%, oil). HPLC-MS: m/z=277.2 (M+1); Rt: 4.19 min.

Workup

  1. customThe crude product was purified by preparative HPLC (54%, oil)

Sources & evidence

ORD record
ord-86b7ab3f23d749bd9e841d572f24a7f1
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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