4-(Trifluoromethyl)benzylamine → HCID 69519056, compound

HRID 1831212Notes

Reaction equation

HRID 1831212 reaction equation
O=C1CCC(=O)N1O[C:9](=[O:27])[C:10]1[CH:15]=[CH:14][C:13]([O:16][C:17](=[O:26])[N:18]([CH3:25])[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:12][CH:11]=1.[F:28][C:29]([F:39])([F:38])[C:30]1[CH:37]=[CH:36][C:33]([CH2:34][NH2:35])=[CH:32][CH:31]=1>>[F:28][C:29]([F:38])([F:39])[C:30]1[CH:37]=[CH:36][C:33]([CH2:34][NH:35][C:9]([C:10]2[CH:11]=[CH:12][C:13]([O:16][C:17](=[O:26])[N:18]([CH3:25])[C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)=[CH:14][CH:15]=2)=[O:27])=[CH:32][CH:31]=1

Participants

3

Reactant 2

HCID 768044-(Trifluoromethyl)benzylamineHCID 865892064-(Methyl-phenyl-carbamoyloxy)-benzoic Acid 2,5-dioxo-pyrrolidin-1-yl Ester

Product 1

HCID 69519056HCID 69519056, compound

Procedure

The title product was prepared from 4-(methyl-phenyl-carbamoyloxy)-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester and 4-trifluoromethyl-benzylamine (94%, white crystals). HPLC-MS: m/z=429.2 (M+1); Rt: 4.35 min.

Sources & evidence

ORD record
ord-a5ec97a242e046b7a2de5c327d44130a
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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