2-Pyridineethanamine → Methyl-phenyl-carbamic Acid 4-(2-pyridin-2-yl-ethylcarbamoyl)-phenyl Ester

HRID 1831216Notes

Reaction equation

HRID 1831216 reaction equation
O=C1CCC(=O)N1O[C:9](=[O:27])[C:10]1[CH:15]=[CH:14][C:13]([O:16][C:17](=[O:26])[N:18]([CH3:25])[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:12][CH:11]=1.[NH2:28][CH2:29][CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][N:32]=1>>[N:32]1[CH:33]=[CH:34][CH:35]=[CH:36][C:31]=1[CH2:30][CH2:29][NH:28][C:9]([C:10]1[CH:11]=[CH:12][C:13]([O:16][C:17](=[O:26])[N:18]([CH3:25])[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)=[CH:14][CH:15]=1)=[O:27]

Participants

3

Reactant 2

HCID 759192-PyridineethanamineHCID 865892064-(Methyl-phenyl-carbamoyloxy)-benzoic Acid 2,5-dioxo-pyrrolidin-1-yl Ester

Product 1

HCID 69518692Methyl-phenyl-carbamic Acid 4-(2-pyridin-2-yl-ethylcarbamoyl)-phenyl Ester

Procedure

The title product was prepared from 4-(methyl-phenyl-carbamoyloxy)-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester and 2-aminoethylpyridine. The crude product was used without further purification (26%, oil). HPLC-MS: m/z=376.2 (M+1); Rt: 2.25 min.

Workup

  1. customThe crude product was used without further purification (26%, oil)

Sources & evidence

ORD record
ord-471627fd307a45e0b920940c1864dc1a
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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