4-Chlorobenzylpiperazine → 4-(4-Chlorobenzyl)piperazine-1-carboxylic Acid 4-(4-trifluoromethylphenoxy)phenyl Ester

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Reaktionsschritte

The hydrochloride of the title compound was prepared from 4-(4-trifluoromethylphenoxy)phenyl chloroformate and 1-(4-chlorobenzyl)piperazine, yield 86%. White crystals, m.p. 232–234° C.; 1H NMR (DMSO-d6): δ 11.92 (br s, 1H), 3 AB-systems: 7.83–7.62 (t-like, 4H) and 7.62–7.48 (d-like, 2H), and 7.32–7.07 (m, 6H); 4.51–3.95 (br s at 4.37 ppm overlapping with br signal at 4.2 ppm, 4H), 3.95–2.95 (br m, 9H: 6H+water); IR (KBr): ν 1717 (C═O) cm−1.

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