Carbamic chloride, N-methyl-N-phenyl- → HCID 10236711, compound

HRID 1831277Notes

Reaction equation

HRID 1831277 reaction equation
[OH:1][N:2]1[C:6]([C:7]2[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][CH:8]=2)=[CH:5][CH:4]=[N:3]1.[CH3:15][N:16]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:17](Cl)=[O:18]>>[CH3:14][O:13][C:10]1[CH:9]=[CH:8][C:7]([C:6]2[N:2]([O:1][C:17](=[O:18])[N:16]([CH3:15])[C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[N:3]=[CH:4][CH:5]=2)=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 22047687HCID 22047687, compound

Product 1

HCID 10236711HCID 10236711, compound

Procedure

The title compound was prepared from 1-hydroxy-5-(4-methoxyphenyl)pyrazole and N-methyl-N-phenylcarbamoyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (38%, yellow crystals).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (38%, yellow crystals)

Sources & evidence

ORD record
ord-0c838d80946e447784a0aaa4c721e3e4
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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