Carbamic chloride, N-methyl-N-phenyl- → HCID 69517290, compound

HRID 1831287Notes

Reaction equation

HRID 1831287 reaction equation
Cl.[OH:2][N:3]1[C:7]([C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][CH:9]=2)=[CH:6][N:5]=[C:4]1[Cl:15].[CH3:16][N:17]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[C:18](Cl)=[O:19]>>[Cl:15][C:4]1[N:3]([O:2][C:18](=[O:19])[N:17]([CH3:16])[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:7]([C:8]2[CH:9]=[CH:10][C:11]([CH3:14])=[CH:12][CH:13]=2)=[CH:6][N:5]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 131725814HCID 131725814, compound

Product 1

HCID 69517290HCID 69517290, compound

Procedure

The title compound was prepared from 1-hydroxy-2-chloro-5-(4-methylphenyl)imidazole, hydrochloride and N-methyl-N-phenylcarbamoyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (80%, oil).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (80%, oil)

Sources & evidence

ORD record
ord-89bb530172d54fe198eba590eb750287
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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