Carbamic chloride, N-methyl-N-phenyl- → HCID 69518469, compound

HRID 1831290Notes

Reaction equation

HRID 1831290 reaction equation
[OH:1][N:2]1[CH:6]=[C:5]([C:7]#[C:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:4]=[N:3]1.[CH3:15][N:16]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:17](Cl)=[O:18]>>[C:9]1([C:8]#[C:7][C:5]2[CH:4]=[N:3][N:2]([O:1][C:17](=[O:18])[N:16]([CH3:15])[C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[CH:6]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 69519054HCID 69519054, compound

Product 1

HCID 69518469HCID 69518469, compound

Procedure

The title compound was prepared from 1-hydroxy-4-phenylethynylpyrazole and N-methyl-N-phenylcarbamoyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (40%, yellow crystals).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (40%, yellow crystals)

Sources & evidence

ORD record
ord-1ef4234329884981a2d1c04186851c6b
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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