Carbamic chloride, N-methyl-N-phenyl- → HCID 10149505, compound

HRID 1831291Notes

Reaction equation

HRID 1831291 reaction equation
Cl.[OH:2][N:3]1[CH:7]=[CH:6][N:5]=[C:4]1[Br:8].[CH3:9][N:10]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:11](Cl)=[O:12]>>[Br:8][C:4]1[N:3]([O:2][C:11](=[O:12])[N:10]([CH3:9])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:7]=[CH:6][N:5]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 131725815HCID 131725815, compound

Product 1

HCID 10149505HCID 10149505, compound

Procedure

The title compound was prepared from 1-hydroxy-2-bromoimidazole, hydrochloride and N-methyl-N-phenylcarbamoyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (63%, oil).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (63%, oil)

Sources & evidence

ORD record
ord-34321f7134b840f184d3f874fa68ed48
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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