Carbamic chloride, N-methyl-N-phenyl- → HCID 10125771, compound

HRID 1831292Notes

Reaction equation

HRID 1831292 reaction equation
Cl.[OH:2][N:3]1[CH:7]=[CH:6][N:5]=[C:4]1[S:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[CH3:15][N:16]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:17](Cl)=[O:18]>>[C:9]1([S:8][C:4]2[N:3]([O:2][C:17](=[O:18])[N:16]([CH3:15])[C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[CH:7]=[CH:6][N:5]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 22047971HCID 22047971, compound

Product 1

HCID 10125771HCID 10125771, compound

Procedure

The title compound was prepared from 1-hydroxy-2-phenylsulfanylimidazole hydrochloride and N-methyl-N-phenylcarbamoyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (61%, oil).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (61%, oil)

Sources & evidence

ORD record
ord-90080db0c13241bc87ab22c34b1158e4
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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