4-Morpholinecarbonyl chloride → HCID 69518006, compound

HRID 1831296Notes

Reaction equation

HRID 1831296 reaction equation
Cl.[OH:2][N:3]1[CH:7]=[CH:6][N:5]=[C:4]1[S:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[N:15]1([C:21](Cl)=[O:22])[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1>>[C:9]1([S:8][C:4]2[N:3]([O:2][C:21]([N:15]3[CH2:20][CH2:19][O:18][CH2:17][CH2:16]3)=[O:22])[CH:7]=[CH:6][N:5]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 22047971HCID 22047971, compound

Product 1

HCID 69518006HCID 69518006, compound

Procedure

The title compound was prepared from 1-hydroxy-2-phenylsulfanylimidazole, hydrochloride and 4-morpholine carbonyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc) (98%, oil).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc) (98%, oil)

Sources & evidence

ORD record
ord-b9957cc7f2e14ad0bf36a37a74576b53
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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