4-Morpholinecarbonyl chloride → HCID 69519763, compound

HRID 1831297Notes

Reaction equation

HRID 1831297 reaction equation
Cl.[OH:2][N:3]1[CH:7]=[CH:6][N:5]=[C:4]1[C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1.[N:16]1([C:22](Cl)=[O:23])[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1>>[CH3:15][O:14][C:11]1[CH:10]=[CH:9][C:8]([C:4]2[N:3]([O:2][C:22]([N:16]3[CH2:21][CH2:20][O:19][CH2:18][CH2:17]3)=[O:23])[CH:7]=[CH:6][N:5]=2)=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 131725812HCID 131725812, compound

Product 1

HCID 69519763HCID 69519763, compound

Procedure

The title compound was prepared from 1-hydroxy-2-(4-methoxyphenyl)imidazole, hydrochloride and 4-morpholine carbonyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc) (49%, crystals).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc) (49%, crystals)

Sources & evidence

ORD record
ord-17635c92daef423e9194552ce7ff1182
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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