4-Morpholinecarbonyl chloride → HCID 69518759, compound

HRID 1831302Notes

Reaction equation

HRID 1831302 reaction equation
[OH:1][N:2]1[CH:6]=[CH:5][C:4]([C:7]2[S:8][CH:9]=[CH:10][CH:11]=2)=[N:3]1.[N:12]1([C:18](Cl)=[O:19])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1>>[S:8]1[CH:9]=[CH:10][CH:11]=[C:7]1[C:4]1[CH:5]=[CH:6][N:2]([O:1][C:18]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)=[O:19])[N:3]=1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 10942807HCID 10942807, compound

Product 1

HCID 69518759HCID 69518759, compound

Procedure

The title compound was prepared from 1-hydroxy-3-(2-thienyl)pyrazole and 4-morpholine carbonyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (75%, crystals).

Workup

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (75%, crystals)

Sources & evidence

ORD record
ord-31a56701d00d4bffa82cc884171dae3d
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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