Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Bromide → 4-(Tetrahydrofuran-2-ylmethyl)-piperazine-1-carboxylic acid 4-(3-chloro-5-trifluoromethylpyridin-2-yloxy)-phenyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Bromide | HCID 253877 | — |
| 반응물 | 1-(Tetrahydro-2-furylmethyl)piperazine | HCID 2737265 | — |
| 반응물 | 4-(3-Chloro-5-trifluoromethylpyridin-2-yloxy)-phenyl chloroformate | HCID 22047691 | — |
| 생성물 | 4-(Tetrahydrofuran-2-ylmethyl)-piperazine-1-carboxylic acid 4-(3-chloro-5-trifluoromethylpyridin-2-yloxy)-phenyl Ester | HCID 69518673 | — |
반응 단계
The hydrochloride of the title compound was prepared from 4-(3-chloro-5-trifluoromethyl-pyridin-2-yloxy)-phenyl chloroformate and 1-(tetrahydrofuran-2-ylmethyl)-piperazine, yield 23%. White crystals, m.p. 98–100° C.; IR (KBr): ν 1731 (C═O) cm−.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07067517B2 |
| 출처 데이터셋 | uspto-grants-2006_06 |
| ORD ID | ord-737e90883b69443482cfb45105924378 |
| 출처 메모 | uspto-grants-2006_06 |