1H-Benzimidazole-2-methanamine → HCID 69518755, compound

HRID 1831380Notes

Reaction equation

HRID 1831380 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[CH2:10][NH2:11].O=C1CCC(=O)N1[O:19][C:20](=O)[C:21]1[CH:26]=[CH:25][C:24]([O:27][C:28](=[O:37])[N:29]([CH3:36])[C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)=[CH:23][CH:22]=1>>[NH:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[CH2:10][NH:11][C:20]([C:21]1[CH:26]=[CH:25][C:24]([O:27][C:28](=[O:37])[N:29]([CH3:36])[C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=2)=[CH:23][CH:22]=1)=[O:19]

Participants

3

Reactant 2

HCID 1458201H-Benzimidazole-2-methanamineHCID 865892064-(Methyl-phenyl-carbamoyloxy)-benzoic Acid 2,5-dioxo-pyrrolidin-1-yl Ester

Product 1

HCID 69518755HCID 69518755, compound

Procedure

The title product was prepared from C-(1H-benzimidazol-2-yl)-methylamine and 4-(methyl-phenyl-carbamoyloxy)-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester. The crude product was subjected to preparative HPLC (method C) (8%, off-white crystals). HPLC-MS m/z=401.1 (M+1), Rt: 2.56 min.

Sources & evidence

ORD record
ord-e2fa4519fb3c49b7ab62befaff01f799
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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