[4-(Benzylsulfamoyl)phenyl]boronic acid → HCID 69519373, compound

HRID 1831408Notes

Reaction equation

HRID 1831408 reaction equation
I[C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9](=[O:18])[N:10]([CH3:17])[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:4][CH:3]=1.[CH2:19]([NH:26][S:27]([C:30]1[CH:35]=[CH:34][C:33](B(O)O)=[CH:32][CH:31]=1)(=[O:29])=[O:28])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:19]([NH:26][S:27]([C:30]1[CH:35]=[CH:34][C:33]([C:2]2[CH:7]=[CH:6][C:5]([O:8][C:9](=[O:18])[N:10]([CH3:17])[C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[CH:4][CH:3]=2)=[CH:32][CH:31]=1)(=[O:28])=[O:29])[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 22047905[4-(Benzylsulfamoyl)phenyl]boronic acidHCID 69517304Methyl-phenyl-carbamic Acid 4-iodo-phenyl Ester

Product 1

HCID 69519373HCID 69519373, compound

Procedure

The title compound was prepared from methyl-phenyl-carbamic acid 4-iodo-phenyl ester and 4-benzylsulfamoylbenzeneboronic acid. The crude product was purified by preparative HPLC (Gilson) (35%, pink crystals).

Workup

  1. customThe crude product was purified by preparative HPLC (Gilson) (35%, pink crystals)

Sources & evidence

ORD record
ord-5ffa92cfd1cd4a50b934150bde35abe2
Source dataset
uspto-grants-2006_06
Patent number
US07067517B2

Reaction notes

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