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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1831431Generated: November 2, 2026

Trifluoroacetic acid → Methyl-phenyl-carbamic Acid 4-[2-(4-imidazol-1-yl-phenoxy)-ethyl]-phenyl Ester

https://huagongshe.com/reaction/1831431

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant1-(p-Hydroxyphenyl)imidazoleHCID 82315—
ReactantMethyl-phenyl-carbamic Acid 4-(2-hydroxy-ethyl)-phenyl EsterHCID 69520342—
ProductMethyl-phenyl-carbamic Acid 4-[2-(4-imidazol-1-yl-phenoxy)-ethyl]-phenyl EsterHCID 6951894262%

Reaction Steps

The title compound was prepared as its TFA salt in 62% yield as an oil using methyl-phenyl-carbamic acid 4-(2-hydroxy-ethyl)-phenyl ester and 4-imidazol-1-yl-phenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067517B2
Source datasetuspto-grants-2006_06
ORD IDord-aa34569d21b741ff8951c9578709cab0
Source noteuspto-grants-2006_06