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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1831432Generated: October 31, 2026

Trifluoroacetic acid → Methyl-phenyl-carbamic Acid 4-{2-[4-(2-dimethylamino-ethyl)-phenoxy]-ethyl}-phenyl Ester

https://huagongshe.com/reaction/1831432

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHordenineHCID 68313—
ReactantMethyl-phenyl-carbamic Acid 4-(2-hydroxy-ethyl)-phenyl EsterHCID 69520342—
ProductMethyl-phenyl-carbamic Acid 4-{2-[4-(2-dimethylamino-ethyl)-phenoxy]-ethyl}-phenyl EsterHCID 6951906192%

Reaction Steps

The title compound was prepared as its TFA salt in 92% yield as an oil using methyl-phenyl-carbamic acid 4-(2-hydroxy-ethyl)-phenyl ester and 4-(2-dimethylaminoethyl)-phenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067517B2
Source datasetuspto-grants-2006_06
ORD IDord-fda42cd6b3f94558b619b33b6eb7fbff
Source noteuspto-grants-2006_06