HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl-phenyl-carbamic Acid 4-hydroxymethyl-phenyl Ester → Methyl-phenyl-carbamic Acid 4-(2-oxo-2H-pyridin-1-ylmethyl)-phenyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl-phenyl-carbamic Acid 4-hydroxymethyl-phenyl Ester | HCID 69518671 | — |
| Reactant | HCID 178516071 | HCID 178516071 | — |
| Product | Methyl-phenyl-carbamic Acid 4-(2-oxo-2H-pyridin-1-ylmethyl)-phenyl Ester | HCID 69518928 | 66% |
Reaction Steps
The title compound was prepared in 66% yield as an oil using methyl-phenyl-carbamic acid 4-hydroxymethyl-phenyl ester and 2-hydroxypyridine. 1H NMR (400 MHz; CDCl3): δ 3.42 (br s, 3H), 5.12 (s, 2H), 6.13 (t, 1H), 6.60 (d, 1H), 7.10 (br s, 2H), 7.22–7.41 (m, 9H); HPLC-MS: m/z=335.2 (M+1); Rt=2.97 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07067517B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-6129aeb0e68a46fdbb0a96f17f2742d4 |
| Source note | uspto-grants-2006_06 |