HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Methyl-phenyl-carbamic Acid 4-[1,2,4]triazol-1-ylmethyl-phenyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | Methyl-phenyl-carbamic Acid 4-hydroxymethyl-phenyl Ester | HCID 69518671 | — |
| Product | Methyl-phenyl-carbamic Acid 4-[1,2,4]triazol-1-ylmethyl-phenyl Ester | HCID 69519634 | 27% |
Reaction Steps
The title compound was prepared as its TFA salt in 27% yield as an oil using methyl-phenyl-carbamic acid 4-hydroxymethyl-phenyl ester and 1,2,4-triazole. 1H NMR (400 MHz; CDCl3): δ 3.42 (br s, 3H), 5.34 (s, 2H), 7.15 (br d, 2H), 7.26–7.43 (m, 7H), 8.10 (s, 1H), 8.38 (s, 1H); HPLC-MS: m/z=309.1 (M+1); Rt=2.74 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07067517B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-8b83d99883bc49428a8406f3030342b1 |
| Source note | uspto-grants-2006_06 |