1-Cyclopropylpropan-1-amine → (1-Cyclopropyl-propyl)-[4-(2,4-dichloro-phenyl)-3-nitro-pyridin-2-yl]-amine

Participants

Role	Name	HCID	Charge
Reactant	1-Cyclopropylpropan-1-amine	HCID 3985879	—
Reactant	2-Chloro-4-(2,4-dichloro-phenyl)-3-nitro-pyridine	HCID 22052102	—
Product	(1-Cyclopropyl-propyl)-[4-(2,4-dichloro-phenyl)-3-nitro-pyridin-2-yl]-amine	HCID 11057630	83%

Reaction Steps

2-Chloro-4-(2,4-dichloro-phenyl)-3-nitro-pyridine (0.34 g, 1.12 mmol) and 1-cyclopropyl-propylamine (0.30 g, 2.24 mmol) were treated substantially as described in Part D of Example 9 to produce 0.26 g (83%) of crude (1-cyclopropyl-propyl)-[4-(2,4-dichloro-phenyl)-3-nitro-pyridin-2-yl]-amine: MS (AP) m/z 366.3 [(M+H)+, 100].

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07067658B2
Source dataset	uspto-grants-2006_06
ORD ID	ord-6ce826d96f8a41c3bb8e53e04aea45ea
Source note	uspto-grants-2006_06