Sodium Dithionite → 4-(2-chloro-4-methoxy-phenyl)-N2-(1-propyl-butyl)-pyridine-2,3-diamine

Participants

Role	Name	HCID	Charge
Reactant	Sodium Dithionite	HCID 24489	—
Reactant	[4-(2-Chloro-4-methoxy-phenyl)-3-nitro-pyridin-2-yl]-(1-propyl-butyl)-amine	HCID 22052147	—
Product	4-(2-chloro-4-methoxy-phenyl)-N2-(1-propyl-butyl)-pyridine-2,3-diamine	HCID 69658299	171.8%

Reaction Steps

[4-(2-Chloro-4-methoxy-phenyl)-3-nitro-pyridin-2-yl]-(1-propyl-butyl)-amine (0.31 g, 0.82 mmol) and Na2S2O4 (1.15 g, 6.62 mmol) were treated substantially as described in Part E of Example 9 to give 0.49 g (100%) 4-(2-chloro-4-methoxy-phenyl)-N2-(1-propyl-butyl)-pyridine-2,3-diamine: MS (AP) m/z 347.9 [(M+H)+, 100].

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07067658B2
Source dataset	uspto-grants-2006_06
ORD ID	ord-9f156d0a898a46048aa73422956a231a
Source note	uspto-grants-2006_06