HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Dithionite → 4-(2-chloro-4-methoxy-phenyl)-N2-(1-cyclobutyl-propyl)-pyridine-2,3-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Dithionite | HCID 24489 | — |
| Reactant | [4-(2-Chloro-4-methoxy-phenyl)-3-nitro-pyridin-2-yl]-(1-cyclobutyl-propyl)-amine | HCID 22052220 | — |
| Product | 4-(2-chloro-4-methoxy-phenyl)-N2-(1-cyclobutyl-propyl)-pyridine-2,3-diamine | HCID 69658165 | 108.4% |
Reaction Steps
[4-(2-Chloro-4-methoxy-phenyl)-3-nitro-pyridin-2-yl]-(1-cyclobutyl-propyl)-amine (0.33 g, 0.88 mmol) and Na2S2O4 (1.33 g, 7.6 mmol) were treated substantially as described in Part E of Example 9 to give 0.33 g (100%) 4-(2-chloro-4-methoxy-phenyl)-N2-(1-cyclobutyl-propyl)-pyridine-2,3-diamine: MS (AP) m/z 345.9 [(M+H)+, 100].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07067658B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-c998d6d687ec434faae778c4103825d4 |
| Source note | uspto-grants-2006_06 |