反应详情

Trifluoro-methanesulfonic acid 4-(4-methoxy-2-methyl-phenyl)-3-nitro-pyridin-2-yl-ester (0.78 g, 1.98 mmol), prepared substantially as described in Part C of Example 67a, and 1-methoxymethyl-propylamine (0.45 g, 4.36 mmol) were treated substantially as described in Part C of Example 67a to produce 27 mg (40%) of [4-(4-methoxy-2-methyl-phenyl)-3-nitro-pyridin-2-yl]-(1-methoxymethyl-propyl)-amine; MS (EI) m/z 346.33 [(M+H)+, 100].

1. additionwere treated substantially