HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Dithionite → 4-(2-chloro-4-trifluoromethyl-phenyl)-N2-(1-cyclopropyl-propyl)-pyridine-2,3-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Dithionite | HCID 24489 | — |
| Reactant | [4-(2-Chloro-4-trifluoromethyl-phenyl)-3-nitro-pyridin-2-yl]-(1-cyclopropyl-propyl)-amine | HCID 22052129 | — |
| Product | 4-(2-chloro-4-trifluoromethyl-phenyl)-N2-(1-cyclopropyl-propyl)-pyridine-2,3-diamine | HCID 69658054 | 94% |
Reaction Steps
[4-(2-Chloro-4-trifluoromethyl-phenyl)-3-nitro-pyridin-2-yl]-(1-cyclopropyl-propyl)-amine (0.55 g, 1.38 mmol) and Na2S2O4 (1.93 g, 11.1 mmol) were treated substantially as in Part E of Example 9 to yield 94% of 4-(2-chloro-4-trifluoromethyl-phenyl)-N2-(1-cyclopropyl-propyl)-pyridine-2,3-diamine: MS (AP) m/z 369.8 [(M+H)+, 100].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07067658B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-06e92bbff0eb4f4cbd1c3bc0ad849cc3 |
| Source note | uspto-grants-2006_06 |