Tin dichloride dihydrate → HCID 69658121, compound

Participants

Reaction Steps

(R)-[4-(2-Chloro-4-dimethylamino-5-fluoro-phenyl)-3-nitro-pyridin-2-yl]-(1-cyclobutyl-ethyl)-amine (326 mg, 0.83 mmol) and SnCl2.H2O (472 mg, 2.5 mmol) were treated substantially as described in Part D of Example 74a to yield 301 mg of crude (R)-4-(2-Chloro-4-dimethylamino-5-fluoro-phenyl)-N2-(1-cyclobutyl-ethyl)-pyridine-2,3-diamine: MS (EI) m/z 363.24 [(M+H)+, 100].

Provenance & Evidence