1-(2-Phenyl-1,3-thiazol-4-yl)ethan-1-one → 2-Methyl-N-(3-{1-[1-(2-phenyl-1,3-thiazol-4-YL)ethyl]-4-piperidinyl}phenyl)propanamide

HRID 1832354Notes

Reaction equation

HRID 1832354 reaction equation
[C:1]1([C:7]2[S:8][CH:9]=[C:10]([C:12](=O)[CH3:13])[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:15][CH:16]([CH3:32])[C:17]([NH:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[CH:21]=1)=[O:18]>>[CH3:15][CH:16]([CH3:32])[C:17]([NH:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH:26]2[CH2:31][CH2:30][N:29]([CH:12]([C:10]3[N:11]=[C:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)[S:8][CH:9]=3)[CH3:13])[CH2:28][CH2:27]2)[CH:21]=1)=[O:18]

Participants

3

Reactant 2

HCID 6048191-(2-Phenyl-1,3-thiazol-4-yl)ethan-1-oneHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 220491162-Methyl-N-(3-{1-[1-(2-phenyl-1,3-thiazol-4-YL)ethyl]-4-piperidinyl}phenyl)propanamide

Procedure

Prepared by Procedure F and Scheme R using 1-(2-phenyl-1,3-thiazol-4-yl)ethanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 434.2 (M+H)+.

Workup

  1. customPrepared by Procedure F and Scheme R

Sources & evidence

ORD record
ord-8597811957c54872b9999df59be59e3b
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

Loading…