2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → HCID 178454456, compound
Reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[C:10]([CH:11]=O)=[CH:9][NH:8][N:7]=1.[CH3:13][CH:14]([CH3:30])[C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[CH:19]=1)=[O:16]>>[CH3:13][CH:14]([CH3:30])[C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]2[CH2:29][CH2:28][N:27]([CH2:11][C:10]3[C:6]([C:2]4[S:1][CH:5]=[CH:4][CH:3]=4)=[N:7][NH:8][CH:9]=3)[CH2:26][CH2:25]2)[CH:19]=1)=[O:16]Participants
3
Procedure
Prepared by Procedure F and Scheme R using 3-(2-thienyl)-1H-pyrazole-4-carbaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 409.1 (M+H)+.
Workup
- customPrepared by Procedure F and Scheme R
Sources & evidence
- ORD record
- ord-665a34b574dc4acea29111ac330b4a81
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07067534B1
Reaction notes
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