5-[3-(trifluoromethoxy)phenyl]furan-2-carbaldehyde → HCID 22049295, compound

HRID 1832406Notes

Reaction equation

HRID 1832406 reaction equation
[F:1][C:2]([F:18])([F:17])[O:3][C:4]1[CH:5]=[C:6]([C:10]2[O:14][C:13]([CH:15]=O)=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1.[CH3:19][CH:20]([CH3:36])[C:21]([NH:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[CH:25]=1)=[O:22]>>[CH3:19][CH:20]([CH3:36])[C:21]([NH:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH:30]2[CH2:35][CH2:34][N:33]([CH2:15][C:13]3[O:14][C:10]([C:6]4[CH:7]=[CH:8][CH:9]=[C:4]([O:3][C:2]([F:1])([F:17])[F:18])[CH:5]=4)=[CH:11][CH:12]=3)[CH2:32][CH2:31]2)[CH:25]=1)=[O:22]

Participants

3

Reactant 2

HCID 7371835-[3-(trifluoromethoxy)phenyl]furan-2-carbaldehydeHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 22049295HCID 22049295, compound

Procedure

Prepared by Procedure F and Scheme R using 5-[3-(trifluoromethoxy)phenyl]-2-furaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 487.2 (M+H)+.

Workup

  1. customPrepared by Procedure F and Scheme R

Sources & evidence

ORD record
ord-b2cc7a7047264e48aa5fb71408f45262
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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