9-ethyl-9H-carbazole-3-carbaldehyde → N-(3-{1-[(9-Ethyl-9H-carbazol-3-YL)methyl]-4-piperidinyl}-4-methylphenyl)-2-methylpropanamide
Reaction equation
[CH2:1]([N:3]1[C:15]2[CH:14]=[CH:13][C:12]([CH:16]=O)=[CH:11][C:10]=2[C:9]2[C:4]1=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH3:2].[CH3:18][CH:19]([CH3:36])[C:20]([NH:22][C:23]1[CH:28]=[CH:27][C:26]([CH3:29])=[C:25]([CH:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[CH:24]=1)=[O:21]>>[CH2:1]([N:3]1[C:15]2[CH:14]=[CH:13][C:12]([CH2:16][N:33]3[CH2:34][CH2:35][CH:30]([C:25]4[CH:24]=[C:23]([NH:22][C:20](=[O:21])[CH:19]([CH3:36])[CH3:18])[CH:28]=[CH:27][C:26]=4[CH3:29])[CH2:31][CH2:32]3)=[CH:11][C:10]=2[C:9]2[C:4]1=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH3:2]Participants
3
Procedure
Prepared by Procedure AA and Scheme AJ using 9-ethyl-9H-carbazole-3-carbaldehyde and 2-methyl-N-[4-methyl-3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 468.1 (M+H)+.
Workup
- customPrepared by Procedure AA and Scheme AJ
Sources & evidence
- ORD record
- ord-728fa90cddb940519bc0f7331ecf02d6
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07067534B1
Reaction notes
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