(1R)-3-chloro-1-phenylpropan-1-ol → HCID 58651342, compound

HRID 1832445Notes

Reaction equation

HRID 1832445 reaction equation
Cl[CH2:2][CH2:3][C@H:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[OH:5].[NH:12]1[CH2:17][CH2:16][CH:15]([C:18]2[CH:19]=[C:20]([NH:24][C:25]([CH:27]3[CH2:29][CH2:28]3)=[O:26])[CH:21]=[CH:22][CH:23]=2)[CH2:14][CH2:13]1>>[OH:5][C@@H:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:3][CH2:2][N:12]1[CH2:17][CH2:16][CH:15]([C:18]2[CH:19]=[C:20]([NH:24][C:25]([CH:27]3[CH2:28][CH2:29]3)=[O:26])[CH:21]=[CH:22][CH:23]=2)[CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 642409(1R)-3-chloro-1-phenylpropan-1-olHCID 22048669N-[3-(4-Piperidinyl)phenyl]cyclopropanecarboxamide

Product 1

HCID 58651342HCID 58651342, compound

Procedure

Prepared by Procedure G and Scheme B1 using (1R)-3-chloro-1-phenyl-1-propanol and N-[3-(4-piperidinyl)phenyl]cyclopropanecarboxamide: ESMS m/e: 379.2 (M+H)+.

Workup

  1. customPrepared by Procedure G and Scheme B1

Sources & evidence

ORD record
ord-b1e753c600a74492ae6b12d5b7e3a76a
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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