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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832448Generated: October 25, 2026

4-Fluorophenylacetyl chloride → 3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}propyl (4-fluorophenyl)acetate

https://huagongshe.com/reaction/1832448

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorophenylacetyl chlorideHCID 3744988—
ReactantN-{3-[1-(3-Hydroxypropyl)-4-piperidinyl]phenyl}-2-methylpropanamideHCID 22048877—
Product3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}propyl (4-fluorophenyl)acetateHCID 22725371—

Reaction Steps

Prepared by Procedure Q1 and Scheme C2 (TEA) using N-{3-[1-(3-hydroxypropyl)-4-piperidinyl]phenyl}-2-methylpropanamide and (4-fluorophenyl)acetyl chloride: ESMS m/e: 441.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-fd1855e6abbb4399af551c6d7908f569
Source noteuspto-grants-2006_06