HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carbonyl chloride → 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl 3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carbonyl chloride | HCID 2736581 | — |
| Reactant | N-(3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamide | HCID 22048659 | — |
| Product | 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl 3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxylate | HCID 22048757 | — |
Reaction Steps
Prepared by Procedure Q1 and Scheme C2 (TEA) using N-{3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarbonyl chloride: Anal. Calcd for C30H35ClFN3O4+CH2Cl2: C, 63.3; H, 6.23; N, 7.33. Found: C, 63.0; H, 6.39; N, 7.03; ESMS m/e: 556.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07067534B1 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-6335beb146e144c7815b8b3dc3ac4448 |
| Source note | uspto-grants-2006_06 |