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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832458Generated: October 26, 2026

5-Methyl-3-phenylisoxazole-4-carbonyl chloride → 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl 5-methyl-3-phenyl-4-isoxazolecarboxylate

https://huagongshe.com/reaction/1832458

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methyl-3-phenylisoxazole-4-carbonyl chlorideHCID 85624—
ReactantN-(3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamideHCID 22048659—
Product4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl 5-methyl-3-phenyl-4-isoxazolecarboxylateHCID 22048639—

Reaction Steps

Prepared by Procedure Q1 and Scheme C2 (TEA) using N-{3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 5-methyl-3-phenyl-4-isoxazolecarbonyl chloride: ESMS m/e: 504.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-486b04a0c86d42fabb3c96b23a9c640d
Source noteuspto-grants-2006_06