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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832460Generated: October 25, 2026

5-Methyl-3-phenylisoxazole-4-carbonyl chloride → 6-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}hexyl 5-methyl-3-phenyl-4-isoxazolecarboxylate

https://huagongshe.com/reaction/1832460

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methyl-3-phenylisoxazole-4-carbonyl chlorideHCID 85624—
ReactantN-{3-[1-(6-Hydroxyhexyl)-4-piperidinyl]phenyl}-2-methylpropanamideHCID 22049040—
Product6-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}hexyl 5-methyl-3-phenyl-4-isoxazolecarboxylateHCID 22049443—

Reaction Steps

Prepared by Procedure Q1 and Scheme C2 (TEA) using N-{3-[1-(6-hydroxyhexyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 5-methyl-3-phenyl-4-isoxazolecarbonyl chloride: ESMS m/e: 532.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-ade2102d96734caf83dd60aba60c17d3
Source noteuspto-grants-2006_06