HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Isoxazolecarbonyl chloride, 3-(2-chlorophenyl)-5-methyl- → 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylbutyl 3-(2-chlorophenyl)-5-methyl-4-isoxazolecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Isoxazolecarbonyl chloride, 3-(2-chlorophenyl)-5-methyl- | HCID 96590 | — |
| Reactant | N-(3-[1-(4-hydroxy-4-phenylbutyl)-4-piperidinyl]phenyl}-2-methylpropanamide | HCID 22048814 | — |
| Product | 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylbutyl 3-(2-chlorophenyl)-5-methyl-4-isoxazolecarboxylate | HCID 20723014 | — |
Reaction Steps
Prepared by Procedure Q1 and Scheme C2 (TEA) using N-{3-[1-(4-hydroxy-4-phenylbutyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3-(2-chlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride: ESMS m/e: 614.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07067534B1 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-cd40f0d151174dcca4f35882e1d2f3a9 |
| Source note | uspto-grants-2006_06 |