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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832467Generated: October 25, 2026

Benzoyl chloride, 3-chloro- → 3-Chloro-N-((1S)-3-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylpropyl)benzamide

https://huagongshe.com/reaction/1832467

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl chloride, 3-chloro-HCID 69252—
ReactantN-(3-(1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl)phenyl)-2-methylpropanamideHCID 69523474—
Product3-Chloro-N-((1S)-3-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylpropyl)benzamideHCID 58651307—

Reaction Steps

Prepared by Procedure Q1 and Scheme AC using N-(3-{1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 3-chlorobenzoyl chloride: ESMS m/e: 518.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-0e954af152f6485c94a64767887541bd
Source noteuspto-grants-2006_06