HCID 22049516, compound → HCID 58651281, compound

HRID 1832478Notes

Reaction equation

HRID 1832478 reaction equation
[NH2:1][C@H:2]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][CH:8]([C:11]2[CH:12]=[C:13]([NH:17][C:18](=[O:22])[CH:19]([CH3:21])[CH3:20])[CH:14]=[CH:15][CH:16]=2)[CH2:7][CH2:6]1.[Cl:29][C:30]1[CH:31]=[C:32]([CH:42]=[C:43]([Cl:45])[CH:44]=1)[O:33][C:34]1[NH:38][C:37]([C:39](Cl)=[O:40])=[CH:36][CH:35]=1>>[Cl:29][C:30]1[CH:31]=[C:32]([CH:42]=[C:43]([Cl:45])[CH:44]=1)[O:33][C:34]1[NH:38][C:37]([C:39]([NH:1][C@H:2]([C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)[CH2:3][CH2:4][N:5]2[CH2:10][CH2:9][CH:8]([C:11]3[CH:16]=[CH:15][CH:14]=[C:13]([NH:17][C:18](=[O:22])[CH:19]([CH3:21])[CH3:20])[CH:12]=3)[CH2:7][CH2:6]2)=[O:40])=[CH:36][CH:35]=1

Participants

3

Reactant 2

HCID 22049516HCID 22049516, compoundHCID 69523474N-(3-(1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl)phenyl)-2-methylpropanamide

Product 1

HCID 58651281HCID 58651281, compound

Procedure

Prepared by Procedure Q1 and Scheme AC using N-(3-{1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 5-(3,5-dichlorophenoxy)-1H-pyrrole-2-carbonyl chloride: ESMS m/e: 634.2 (M+H)+.

Workup

  1. customPrepared by Procedure Q1 and Scheme AC

Sources & evidence

ORD record
ord-8f3a27f7097c4b7e90671e070a589514
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

Loading…