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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832556Generated: October 31, 2026

2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → 2-Methyl-N-(3-{1-[(2S)-2-methyl-3-(2,4,5-trifluorophenoxy)propyl]-4-piperidinyl}phenyl)propanamide

https://huagongshe.com/reaction/1832556

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 16757255—
Reactant1-{[(2R)-3-chloro-2-methylpropyl]oxy}-2,4,5-trifluorobenzeneHCID 69523865—
Product2-Methyl-N-(3-{1-[(2S)-2-methyl-3-(2,4,5-trifluorophenoxy)propyl]-4-piperidinyl}phenyl)propanamideHCID 58651277—

Reaction Steps

Prepared by Procedure G and Scheme B1 using 1-{[(2R)-3-chloro-2-methylpropyl]oxy}-2,4,5-trifluorobenzene and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 449.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-be9f187c5a664ceaa756db2792be37ef
Source noteuspto-grants-2006_06