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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1832561Generated: November 2, 2026

2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → N-(3-{1-[(2S)-3-(2-Fluorophenoxy)-2-methylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide

https://huagongshe.com/reaction/1832561

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 16757255—
Reactant1-{[(2R)-3-Chloro-2-methylpropyl]oxy}-2-fluorobenzeneHCID 69523805—
ProductN-(3-{1-[(2S)-3-(2-Fluorophenoxy)-2-methylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamideHCID 58651273—

Reaction Steps

Prepared by Procedure G and Scheme B1 using 1-{[(2R)-3-chloro-2-methylpropyl]oxy}-2-fluorobenzene and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 413.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07067534B1
Source datasetuspto-grants-2006_06
ORD IDord-5cf19508b5e244838a341be424571b13
Source noteuspto-grants-2006_06