2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → HCID 58651308, compound

HRID 1832571Notes

Reaction equation

HRID 1832571 reaction equation
Cl[CH2:2][C@@H:3]([CH3:13])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[Br:12].[CH3:14][CH:15]([CH3:31])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)[CH:20]=1)=[O:17]>>[Br:12][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[O:5][CH2:4][C@H:3]([CH3:13])[CH2:2][N:28]1[CH2:29][CH2:30][CH:25]([C:21]2[CH:20]=[C:19]([NH:18][C:16](=[O:17])[CH:15]([CH3:14])[CH3:31])[CH:24]=[CH:23][CH:22]=2)[CH2:26][CH2:27]1

Participants

3

Reactant 2

HCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 86611005HCID 86611005, compound

Product 1

HCID 58651308HCID 58651308, compound

Procedure

Prepared by Procedure G and Scheme B1 using 2-bromophenyl (2S)-3-chloro-2-methylpropyl ether and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 473.0 (M+H)+.

Workup

  1. customPrepared by Procedure G and Scheme B1

Sources & evidence

ORD record
ord-cdd3a3b1d4c64bd2bb1266216be511a4
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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