N-methyl-N-phenyl-hydrazine → 2-Methyl-N-(3-{1-[3-(1-methyl-2-phenyl-1H-indol-3-YL)propyl]-4-piperidinyl}phenyl)propanamide

HRID 1832589Notes

Reaction equation

HRID 1832589 reaction equation
[CH3:1][CH:2]([CH3:30])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][CH2:21][C:22](=O)[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4].[CH3:31][N:32]([C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)N>>[CH3:1][CH:2]([CH3:30])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][C:21]3[C:39]4[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=4)[N:32]([CH3:31])[C:22]=3[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4]

Participants

3

Reactant 2

HCID 36299N-methyl-N-phenyl-hydrazineHCID 220493932-methyl-N-(3-[1-(5-oxo-5-phenylpentyl)-4-piperidinyl]phenyl}propanamide

Product 1

HCID 220495282-Methyl-N-(3-{1-[3-(1-methyl-2-phenyl-1H-indol-3-YL)propyl]-4-piperidinyl}phenyl)propanamide

Procedure

Prepared by Procedure E and Scheme M using 2-methyl-N-{3-[1-(5-oxo-5-phenylpentyl)-4-piperidinyl]phenyl}propanamide and 1-methyl-1-phenylhydrazine: ESMS m/e: 495.3 (M+H)+.

Workup

  1. customPrepared by Procedure E and Scheme M

Sources & evidence

ORD record
ord-02f60b85cefb4976a3a9d941b28af6df
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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