N-methyl-N-phenyl-hydrazine → 2-Methyl-N-(3-{1-[4-(1-methyl-2-phenyl-1H-indol-3-YL)butyl]-4-piperidinyl}phenyl)propanamide

HRID 1832595Notes

Reaction equation

HRID 1832595 reaction equation
[CH3:1][CH:2]([CH3:31])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23](=O)[C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4].[CH3:32][N:33]([C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1)N>>[CH3:1][CH:2]([CH3:31])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][CH2:21][C:22]3[C:40]4[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=4)[N:33]([CH3:32])[C:23]=3[C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4]

Participants

3

Reactant 2

HCID 36299N-methyl-N-phenyl-hydrazineHCID 220488102-methyl-N-(3-[1-(6-oxo-6-phenylhexyl)-4-piperidinyl]phenyl}propanamide

Product 1

HCID 220490322-Methyl-N-(3-{1-[4-(1-methyl-2-phenyl-1H-indol-3-YL)butyl]-4-piperidinyl}phenyl)propanamide

Procedure

Prepared by Procedure E and Scheme M using 2-methyl-N-{3-[1-(6-oxo-6-phenylhexyl)-4-piperidinyl]phenyl}propanamide and 1-methyl-1-phenylhydrazine: ESMS m/e: 508.3 (M+H)+.

Workup

  1. customPrepared by Procedure E and Scheme M

Sources & evidence

ORD record
ord-cc42d9c793e742c984c353009c514643
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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