4-Methylphenylhydrazine monohydrochloride → 2-Methyl-N-(3-{1-[2-(5-methyl-2-phenyl-1H-indol-3-YL)ethyl]-4-piperidinyl}phenyl)propanamide

HRID 1832597노트

반응식

HRID 1832597 반응식
[CH3:1][CH:2]([CH3:29])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][C:21](=O)[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4].Cl.[CH3:31][C:32]1[CH:37]=[CH:36][C:35]([NH:38]N)=[CH:34][CH:33]=1>>[CH3:1][CH:2]([CH3:29])[C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]2[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][C:20]3[C:36]4[C:35](=[CH:34][CH:33]=[C:32]([CH3:31])[CH:37]=4)[NH:38][C:21]=3[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH2:14][CH2:13]2)[CH:7]=1)=[O:4]

참가 물질

3

반응물 2

HCID 125044-Methylphenylhydrazine monohydrochlorideHCID 220490202-methyl-N-{3-[1-(4-oxo-4-phenylbutyl)-4-piperidinyl]phenyl}propanamide

생성물 1

HCID 220486132-Methyl-N-(3-{1-[2-(5-methyl-2-phenyl-1H-indol-3-YL)ethyl]-4-piperidinyl}phenyl)propanamide

실험 절차

Prepared by Procedure E and Scheme M using 2-methyl-N-{3-[1-(4-oxo-4-phenylbutyl)-4-piperidinyl]phenyl}propanamide and 1-(4-methylphenyl)hydrazine hydrochloride: ESMS m/e: 480.2 (M+H)+.

후처리

  1. customPrepared by Procedure E and Scheme M

출처 및 근거

ORD 기록
ord-cfbf0b482e13444bb5b2c78257c35c49
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067534B1

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