4'-Bromo-4-chlorobutyrophenone → HCID 22048619, compound

HRID 1832682Notes

Reaction equation

HRID 1832682 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:13])[CH2:9][CH2:10][CH2:11]Cl)=[CH:4][CH:3]=1.[NH:14]1[CH2:19][CH2:18][CH:17]([C:20]2[CH:21]=[C:22]([NH:26][C:27](=[O:30])[CH2:28][CH3:29])[CH:23]=[CH:24][CH:25]=2)[CH2:16][CH2:15]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:13])[CH2:9][CH2:10][CH2:11][N:14]2[CH2:19][CH2:18][CH:17]([C:20]3[CH:21]=[C:22]([NH:26][C:27](=[O:30])[CH2:28][CH3:29])[CH:23]=[CH:24][CH:25]=3)[CH2:16][CH2:15]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 783174'-Bromo-4-chlorobutyrophenoneHCID 22048836N-[3-(4-Piperidinyl)phenyl]propanamide

Product 1

HCID 22048619HCID 22048619, compound

Procedure

Prepared by Procedure K and Scheme B1 using 1-(4-bromophenyl)-4-chloro-1-butanone and N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 457.1 (M+H)+.

Workup

  1. customPrepared by Procedure K and Scheme B1

Sources & evidence

ORD record
ord-fea23837b79c47fe9ad12c3a078ec1a2
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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