22620-38-8 → N-(3-{1-[4-Oxo-4-(4-phenoxyphenyl)butyl]-4-piperidinyl}phenyl)propanamide

HRID 1832685Notes

Reaction equation

HRID 1832685 reaction equation
Cl[CH2:2][CH2:3][CH2:4][C:5]([C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:9][CH:8]=1)=[O:6].[NH:20]1[CH2:25][CH2:24][CH:23]([C:26]2[CH:27]=[C:28]([NH:32][C:33](=[O:36])[CH2:34][CH3:35])[CH:29]=[CH:30][CH:31]=2)[CH2:22][CH2:21]1>>[O:6]=[C:5]([C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:9][CH:8]=1)[CH2:4][CH2:3][CH2:2][N:20]1[CH2:25][CH2:24][CH:23]([C:26]2[CH:27]=[C:28]([NH:32][C:33](=[O:36])[CH2:34][CH3:35])[CH:29]=[CH:30][CH:31]=2)[CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 418028722620-38-8HCID 22048836N-[3-(4-Piperidinyl)phenyl]propanamide

Product 1

HCID 22049474N-(3-{1-[4-Oxo-4-(4-phenoxyphenyl)butyl]-4-piperidinyl}phenyl)propanamide

Procedure

Prepared by Procedure K and Scheme B1 using 4-chloro-1-(4-phenoxyphenyl)-1-butanone and N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 471.2 (M+H)+.

Workup

  1. customPrepared by Procedure K and Scheme B1

Sources & evidence

ORD record
ord-b4d6494df57141cd8b4d94bf8f8bbb0e
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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