4-Chloro-3',4'-dimethylbutyrophenone → N-(3-{1-[4-(3,4-Dimethylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl)propanamide

HRID 1832692노트

반응식

HRID 1832692 반응식
Cl[CH2:2][CH2:3][CH2:4][C:5]([C:7]1[CH:12]=[CH:11][C:10]([CH3:13])=[C:9]([CH3:14])[CH:8]=1)=[O:6].[NH:15]1[CH2:20][CH2:19][CH:18]([C:21]2[CH:22]=[C:23]([NH:27][C:28](=[O:31])[CH2:29][CH3:30])[CH:24]=[CH:25][CH:26]=2)[CH2:17][CH2:16]1>>[CH3:14][C:9]1[CH:8]=[C:7]([C:5](=[O:6])[CH2:4][CH2:3][CH2:2][N:15]2[CH2:20][CH2:19][CH:18]([C:21]3[CH:22]=[C:23]([NH:27][C:28](=[O:31])[CH2:29][CH3:30])[CH:24]=[CH:25][CH:26]=3)[CH2:17][CH2:16]2)[CH:12]=[CH:11][C:10]=1[CH3:13]

참가 물질

3

반응물 2

HCID 987424-Chloro-3',4'-dimethylbutyrophenoneHCID 22048836N-[3-(4-Piperidinyl)phenyl]propanamide

생성물 1

HCID 22049104N-(3-{1-[4-(3,4-Dimethylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl)propanamide

실험 절차

Prepared by Procedure K and Scheme B1 using 4-chloro-1-(3,4-dimethylphenyl)-1-butanone and N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 407.2 (M+H)+.

후처리

  1. customPrepared by Procedure K and Scheme B1

출처 및 근거

ORD 기록
ord-803a221cd1744f54b487d9f502aaa309
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067534B1

반응 노트

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