5-Chloro-1-[2-(trifluoromethyl)phenyl]pentan-1-one → HCID 22048685, compound

HRID 1832708Notes

Reaction equation

HRID 1832708 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[C:14]([F:17])([F:16])[F:15])=[O:7].[NH:18]1[CH2:23][CH2:22][CH:21]([C:24]2[CH:25]=[C:26]([NH:30][C:31](=[O:34])[CH2:32][CH3:33])[CH:27]=[CH:28][CH:29]=2)[CH2:20][CH2:19]1>>[O:7]=[C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[C:14]([F:17])([F:16])[F:15])[CH2:5][CH2:4][CH2:3][CH2:2][N:18]1[CH2:23][CH2:22][CH:21]([C:24]2[CH:25]=[C:26]([NH:30][C:31](=[O:34])[CH2:32][CH3:33])[CH:27]=[CH:28][CH:29]=2)[CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 220486925-Chloro-1-[2-(trifluoromethyl)phenyl]pentan-1-oneHCID 22048836N-[3-(4-Piperidinyl)phenyl]propanamide

Product 1

HCID 22048685HCID 22048685, compound

Procedure

Prepared by Procedure K and Scheme B1 using 5-chloro-1-[2-(trifluoromethyl)phenyl]-1-pentanone and N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 461.2 (M+H)+.

Workup

  1. customPrepared by Procedure K and Scheme B1

Sources & evidence

ORD record
ord-40b51f751d3642b79150f63a0a6e7574
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

Loading…