N-[3-(4-Piperidinyl)phenyl]cyclopropanecarboxamide → HCID 22048702, compound

HRID 1832712Notes

Reaction equation

HRID 1832712 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[F:14])=[O:7].[NH:15]1[CH2:20][CH2:19][CH:18]([C:21]2[CH:22]=[C:23]([NH:27][C:28]([CH:30]3[CH2:32][CH2:31]3)=[O:29])[CH:24]=[CH:25][CH:26]=2)[CH2:17][CH2:16]1>>[F:14][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=1[C:6](=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2][N:15]1[CH2:20][CH2:19][CH:18]([C:21]2[CH:22]=[C:23]([NH:27][C:28]([CH:30]3[CH2:31][CH2:32]3)=[O:29])[CH:24]=[CH:25][CH:26]=2)[CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 22048669N-[3-(4-Piperidinyl)phenyl]cyclopropanecarboxamideHCID 220488005-Chloro-1-(2-fluorophenyl)-1-oxopentane

Product 1

HCID 22048702HCID 22048702, compound

Procedure

Prepared by Procedure K and Scheme B1 using 5-chloro-1-(2-fluorophenyl)-1-pentanone and N-[3-(4-piperidinyl)phenyl]cyclopropanecarboxamide: ESMS m/e: 423.1 (M+H)+.

Workup

  1. customPrepared by Procedure K and Scheme B1

Sources & evidence

ORD record
ord-f1fed66506e14fc9b2a668d5018c21b0
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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