4-nitrophenyl(4S)-4-(3,4-difluorophenyl)-2-oxo-1,3-oxazolidine-3-carboxylate → HCID 58651331, compound

HRID 1832727Notes

Reaction equation

HRID 1832727 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C@H:9]2[CH2:13][O:12][C:11](=[O:14])[N:10]2[C:15]([O:17]C2C=CC([N+]([O-])=O)=CC=2)=O)[CH:5]=[CH:6][C:7]=1[F:8].[NH2:27][CH2:28][CH2:29][CH2:30][N:31]1[CH2:36][CH2:35][CH:34]([C:37]2[CH:38]=[C:39]([NH:43][C:44](=[O:48])[CH:45]([CH3:47])[CH3:46])[CH:40]=[CH:41][CH:42]=2)[CH2:33][CH2:32]1>>[F:1][C:2]1[CH:3]=[C:4]([C@H:9]2[CH2:13][O:12][C:11](=[O:14])[N:10]2[C:15]([NH:27][CH2:28][CH2:29][CH2:30][N:31]2[CH2:36][CH2:35][CH:34]([C:37]3[CH:42]=[CH:41][CH:40]=[C:39]([NH:43][C:44](=[O:48])[CH:45]([CH3:46])[CH3:47])[CH:38]=3)[CH2:33][CH2:32]2)=[O:17])[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 155126544-nitrophenyl(4S)-4-(3,4-difluorophenyl)-2-oxo-1,3-oxazolidine-3-carboxylateHCID 16757470N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}2-methylpropanamide

Product 1

HCID 58651331HCID 58651331, compound

Procedure

Prepared by Procedure AF and Scheme H using 4-nitrophenyl (4S)-4-(3,4-difluorophenyl)-2-oxo-1,3-oxazolidine-3-carboxylate and N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}-2-methylpropanamide: ESMS m/e: 529.1 (M+H)+.

Workup

  1. customPrepared by Procedure AF and Scheme H

Sources & evidence

ORD record
ord-083bbcbf7535493280df36dad9ea2f86
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

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