[(4-Chlorobutyl)sulfanyl]benzene → N-(3-{1-[4-(Phenylsulfanyl)butyl]-4-piperidinyl}phenyl)propanamide
Reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][S:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[NH:13]1[CH2:18][CH2:17][CH:16]([C:19]2[CH:20]=[C:21]([NH:25][C:26](=[O:29])[CH2:27][CH3:28])[CH:22]=[CH:23][CH:24]=2)[CH2:15][CH2:14]1>>[C:7]1([S:6][CH2:5][CH2:4][CH2:3][CH2:2][N:13]2[CH2:18][CH2:17][CH:16]([C:19]3[CH:20]=[C:21]([NH:25][C:26](=[O:29])[CH2:27][CH3:28])[CH:22]=[CH:23][CH:24]=3)[CH2:15][CH2:14]2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1Participants
3
Procedure
Prepared by Procedure G and Scheme B1 using [(4-chlorobutyl)sulfanyl]benzene and N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 396.8 (M+H)+.
Workup
- customPrepared by Procedure G and Scheme B1
Sources & evidence
- ORD record
- ord-ede0bf9147204b629b405efaac42c5eb
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07067534B1
Reaction notes
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